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Abstract #2737

Simultaneous Vessel Size and Blood Volume Measurement in a Human Tumor Outside the Brain

Stefanie Remmele1, Janine Ring2, Julien Sngas1, Walter Heindel2, Wolfgang E. Berdel3, Christoph Bremer4, Thorsten Persigehl2

1Philips Research Europe, Hamburg, Germany; 2Department of Radiology, University of Muenster, Muenster, Germany; 3Department of Oncology, University of Muenster, Muenster, Germany; 4Department of Radiology, Franziskus Hospital, Muenster, Germany

This work presents results from the first simultaneous steady-state blood volume and vessel size measurement in a human tumor outside the brain (phleomorphic sarcoma in the pubic bone). Images were free of artifacts, sequence timing allowed for appropriate coverage of the signal decays pre and post injection and the dR2*/dR2 values of the tumor were sufficiently high to generate robust physiologic maps, which appeared to be independent from contrast agent washout.