Stefanie Remmele1,
Janine Ring2, Julien Sngas1, Walter Heindel2,
Wolfgang E. Berdel3, Christoph Bremer4, Thorsten
Persigehl2
1Philips Research Europe, Hamburg,
Germany; 2Department of Radiology, University of Muenster,
Muenster, Germany; 3Department of Oncology, University of
Muenster, Muenster, Germany; 4Department of Radiology, Franziskus
Hospital, Muenster, Germany
This
work presents results from the first simultaneous steady-state blood volume
and vessel size measurement in a human tumor outside the brain (phleomorphic
sarcoma in the pubic bone). Images were free of artifacts, sequence timing
allowed for appropriate coverage of the signal decays pre and post injection
and the dR2*/dR2 values of the tumor were sufficiently high to generate
robust physiologic maps, which appeared to be independent from contrast agent
washout.