Anna Rydhg1, Matthias J. P. van Osch2, Markus Nilsson1, Jimmy Ltt3, Freddy Sthlberg1,4, Ronnie Wirestam1, Linda Knutsson1
1Department of Medical Radiation Physics, Lund University, Lund, Sweden; 2Department of Radiology, LUMC, Leiden, Netherlands; 3Department of Image and function, University Hospital Lund, Lund, Sweden; 4Department of Diagnostic Radiology, Lund University, Lund, Sweden
Intravoxel Incoherent Motion (IVIM) is a non-invasive method which has the potential to quantify perfusion parameters such as CBV and CBF from signal-versus-b data. Simulations was performed usinga synthetic voxel consisting of four different compartments (tissue, CSF, arterial and venous blood ) for comparison of the expected signal curves at three field strength (1.5, 3 and 7 T). Confirmation of the simulated results was obtained from in vivo measurements on a volunteer. We conclude that for higher field strengths the relative contribution from venous blood decreases suggesting that IVIM at 7 T would primarily reflect arterial blood volume.