Boris Odintsov1, Vadim Aleksandrovich
Atsarkin2, Viktor Demidov3, Andrey Kaul4,
Mariya Popova4,
1Biomedical Imaging Center, University
of Illinois , Urbana-Champaign, IL, United States; 2IRE RAN,
Moscow, Russian Federation; 3IRE RAN, Russian Federation; 4Moscow
University, Russian Federation; 5UIUC, IL, United States; 6University
of Illinois, Urbana-Champaign, IL, United States
New
nanomaterials recently synthesized in our group are lanthanum manganite doped
with silver ions. The unique feature of the doped manganites is the
possibility to control their Curie temperature in the range of tumor
hyperthermia interest (41-43oC). At its Curie temperature, a ferromagnetic
particle loses its magnetic properties; this metal-insulator phase transition
is tunable and reversible. New ferromagnetic particles adopt the
superparamagnetic behavior and are comparable to iron oxide as an MRI
contrast agents. The goal of this presentation is to introduce newly
synthesized nanomaterials and create a new platform for highly controllable
hyperthermia cancer therapy and imaging.
Keywords