Abstract #2809

Multi-Slice Parametric Mapping in Prostate DCE-MRI

Ryan Alexander Priest¹, Xin Li², Ian J. Tagge², William J. Woodward², Tomasz M. Beer^3,4, Charles S. Springer, Jr.^2,4, Mark G. Garzotto^5,6

¹Diagnostic Radiology, Oregon Health & Science University, Portland, OR, United States; ²Advanced Imaging Research Center, Oregon Health & Science University, Portland, OR, United States; ³Hematology/Oncology, Oregon Health & Science University, Portland, OR, United States; ⁴Knight Cancer Institute, Oregon Health & Science University, Portland, OR, United States; ⁵Urology, Oregon Health & Science University, Portland, OR, United States; ⁶Portland VA Medical Center, Portland, OR, United States

Pharmacokinetic analysis of data generated using Dynamic-Contrast-Enhanced MRI (DCE-MRI) has proven to be a valuable tool in the evaluation of the vascular pathophysiology of prostate adenocarcinoma. With improved hardware, multi-slice parametric mapping has become feasible and could provide valuable insight to complement conventional T2*-weighted images. In this study multi-slice parametric mapping was performed with DCE-MRI data using both the standard model (SM) and the first generation shutter-speed model (SSM1). Parametric maps were then compared with biopsy results.