(ISMRM 2010) A Slice-Selective B1+-Insensitive Composite Pulse Design for Improved Excitation Uniformity at 7 T
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Abstract #2858

A Slice-Selective B1+-Insensitive Composite Pulse Design for Improved Excitation Uniformity at 7 T

Jay Moore1,2, Marcin Jankiewicz1,3, Adam W. Anderson1,4, John C. Gore1,4

1Institute of Imaging Science, Vanderbilt University, Nashville, TN, United States; 2Department of Physics and Astronomy, Vanderbilt University, Nashville, TN, United States; 3Department of Radiology and Radiological Sciences, Vanderbilt University, Nashville, TN, United States; 4Department of Biomedical Engineering, Vanderbilt University, Nashville, TN, United States


Numerical optimization of the amplitudes and phases of a series of block-shaped sub-pulses was used to generate a 1.2 kHz bandwidth, 90 excitation pulse that is highly insensitive to the variations in the RF transmission field observed in the human brain at 7 T. This pulse serves as an example of the value of RF pulse design in providing an effective and cost-free alternative to technologies such as multiple-channel transmission for the purpose of achieving flip-angle uniformity at high field.

Keywords

pulseoptimizedslicefrequencybandwidthexcitationfielduniformitycompositegridinsensitivemagnetizationmagnitudesprofilespulsesselective