Jay Moore1,2, Marcin Jankiewicz1,3,
Adam W. Anderson1,4, John C. Gore1,4
1Institute of Imaging Science,
Vanderbilt University, Nashville, TN, United States; 2Department
of Physics and Astronomy, Vanderbilt University, Nashville, TN, United
States; 3Department of Radiology and Radiological Sciences,
Vanderbilt University, Nashville, TN, United States; 4Department
of Biomedical Engineering, Vanderbilt University, Nashville, TN, United
States
Numerical
optimization of the amplitudes and phases of a series of block-shaped
sub-pulses was used to generate a 1.2 kHz bandwidth, 90 excitation pulse
that is highly insensitive to the variations in the RF transmission field
observed in the human brain at 7 T.
This pulse serves as an example of the value of RF pulse design in
providing an effective and cost-free alternative to technologies such as
multiple-channel transmission for the purpose of achieving flip-angle
uniformity at high field.