Ronald J. Beyers1, Yaqin Xu1,
Michael Salerno2, Stuart S. Berr3, Craig H. Meyer1,
Frederick H. Epstein1,3, Brent A. French1,2
1Biomedical Engineering, University of
Virginia, Charlottesville, VA, United States; 2School of Medicine,
University of Virginia, Charlottesville, VA, United States; 3Radiology,
University of Virginia, Charlottesville, VA, United States
T2w
MRI of the heart allows imaging post-infarct myocardial edema -- a key
indicator of area at risk and possibly salvagable tissue. For high-field, 7 Tesla imaging in mice, we
compared composite and adiabatic RF pulses in T2-Prep sequences. By simulation, phantom and in vivo imaging,
we developed a flexible adiabatic T2-Prep method for whole-heart imaging of
myocardial edema from onset within hours through resolution past the 20 day
point.