Zoomed Spin-Echo Echo Volumar Imaging of the Mouse Brain in Vivo Using Adiabatic Pulses

Julien Flament¹, Sidi Mohamed Ould Ahmed Ghaly¹, Benjamin Marty¹, Cline Giraudeau¹, Sbastien Mriaux¹, Gilles Bloch¹, Denis Le Bihan¹, Franck Lethimonnier¹, Julien Valette¹, Fawzi Boumezbeur¹

Many developments in the field of fast preclinical imaging are based on EVI sequences. We propose here an optimized protocol designed for preclinical in vivo imaging combining a quadrature surface coil with a zoomed Spin Echo EVI sequence using two orthogonal slice-selective adiabatic pulses (designated as ZEVIA) for volume selection. Brain coverage and time resolution are improved substantially without any drawbacks in the mouse brain in vivo at 7T.