Fat
has a complex spectral composition, which causes its signal to dephase and
decay noticeably even over short intervals. The influence of these effects on
the extent of fat suppression reached in two-point Dixon imaging is evaluated in this work and
is found to strongly depend on the choice of echo times. Moreover, it is
shown how more complex spectral models of fat may be incorporated into a
generalized two-point Dixon
method, with which a more uniform degree of fat suppression is achieved
across a range of relevant echo times.