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Abstract #2949

Fast T1/B1 Mapping Using Multiple Dual TR RF-Spoiled Steady-State Gradient-Echo Sequences

Tobias Voigt1, Stefanie Remmele2, Ulrich Katscher2, Olaf Doessel1

1Institute of Biomedical Engineering, University of Karlsruhe, Karlsruhe, Germany; 2Philips Research Europe, Hamburg, Germany

Efficient and accurate baseline T1 and B1 quantification is a pre-requisite for standardized and clinical Dynamic Contrast-Enhanced MRI (DCE-MRI). This study investigates a new approach called Multiple TR B1/T1 Mapping (MTM), capable of fast, simultaneous B1 and T1 mapping. In this work, MTM is analysed with respect to its T1 mapping performance in comparison with an inversion recovery reference sequence and in due consideration of the limited time allowed in a clinical set-up. In calibrated phantom measurements, MTM T1 mapping was found to be more accurate than IR-TSE, inter alia due to its intrinsic B1 correction mechanism.