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Abstract #2969

Single-Shot Proton Density, T1 and T2 Quantification with Radial IR TrueFISP: Effect of Magnetization Transfer and Long RF Pulses

Philipp Ehses1,2, Vikas Gulani3, Stephen Yutzy3, Nicole Seiberlich3, Peter Michael Jakob1,2, Mark A. Griswold3

1Dept. of Experimental Physics 5, Universitt Wrzburg, Wrzburg, Germany; 2Research Center Magnetic Resonance Bavaria (MRB), , Wrzburg, Germany; 3Department of Radiology, Case Western Reserve University and University Hospitals of Cleveland, Cleveland, OH, United States

The IR TrueFISP sequence has been shown to be a promising approach for the simultaneous quantification of proton density, T1 and T2 maps. For accurate quantification, segmentation is usually necessary, leading to an increase in scan time. In this work, a full set of parameter maps was obtained in a single-shot by combining the IR TrueFISP sequence with a golden-ratio based radial trajectory and using extensive view-sharing. The effects of both magnetization transfer and the violated instantaneous RF assumption on parameter quantification were further analyzed by prolonging the RF pulses and TR (thereby reducing RF power and thus MT).