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Abstract #2980

Detection of Short T2 Component in Brain by SWIFT

Lauri Juhani Lehto1, Djaudat Idiyatullin2, Curtis Andrew Corum2, Michael Garwood2, Olli Heikki Grhn1

1A. I. Virtanen Institute for Molecular Medicine, University of Kuopio, Kuopio, Eastern Finland, Finland; 2Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, MN, United States

The aim of this work was to directly detect signal from the short T2 component in the brain using the SWIFT sequence that allows almost simultaneous excitation and detection. To detect the short T2 component, the overwhelming long T2 component signal was suppressed either by using long adiabatic inversion pulses or by suppressing the short T2 component and subtracting that from a normal SWIFT image. Results show relative enhancement of white matter structures in the brain. The contrast in the latter approach is interpreted to have a contribution also from MTC and thus represents combined direct and indirect detection of the short T2 pool.