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Abstract #2993

Magnetization Transfer Contrast Enhancement Due to Intermolecular Multiple Quantum Coherences - Quantitative Analysis and Tissue Dependency

Sebastian Baier1, Stefan Kirsch1, Lothar R. Schad1

1Department of Computer Assisted Clinical Medicine, Heidelberg University, Mannheim, Germany

This work shows a quantitative analysis of magnetization transfer contrast (MTC) enhancement due to intermolecular multiple quantum coherences (iMQC). Therefore a measurement over a wide range of offset frequencies of the MT pulses was performed for different orders of iMQCs. This data was analyzed by fitting both the standard MT 2 Pool model and a modified model including the order of coherence of the iMQCs. Moreover the tissue dependency of the contrast enhancement was investigated.