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Abstract #2996

Orientation Dependence of Magnetization Transfer in Human White Matter.

Dirk K. Mller1, Andr Pampel1, Harald E. Mller1

1Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany

We present an investigation of the dependence of quantitative magnetization transfer (qMT) on fibre orientation. QMT parameters obtained from experiments using pulsed off-resonance irradiation were correlated to the orientation of the diffusion tensor obtained from DTI data. In particular, we observed a correlation between the fiber orientation with respect to B0 and the transverse relaxation rate of the semi-solid pool (T2b).