Min-Sun Son1, Weitian Chen2, Eric
Han2, Atsushi Takahashi2, Stuart Goodman3,
Marc Levenston4, Garry Gold5
1Bioengineering, Stanford University,
Stanford, CA, United States; 2GE Healthcare; 3Orthopaedic
Surgery, Stanford University; 4Mechanical Engineering, Stanford
University; 5Radiology, Stanford University
T1ρ
and T2 measurements were taken in the anterior, body, and posterior part of
degenerated meniscal specimens using 3D MAPSS sequence with short echo times.
Consistent variations were observed; T1ρ and T2 values were
significantly shorter in the central body than either the anterior or
posterior horn in both medial and lateral menisci, with the lateral menisci
exhibiting greater variations among regions.
A strong, positive correlation between T1ρ and T2 was also found
for all pooled regions. Determining such relationship between the two time
constants and linking it to the degenerative state of the meniscus will be
useful in early detection of osteoarthritis.