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Abstract #3188

Quantitative Reproducibility Initial Study of T1 Rho at 3T

David W. Stanley1, Kameron R. Shahid2, Joel P. Felmlee2, Kimberly K. Amrami2, Eric T. Han3, Dan W. Rettmann4

1MR, GE Healthcare, Proctor, MN, United States; 2Radiology, Mayo Clinic, Rochester, MN, United States; 3Applied Science Laboratory, GE Healthcare, Menlo Park, CA, United States; 4Applied Science Laboratory, GE Healthcare, Rochester , MN, United States

Osteoarthritis is a prevalent degenerative joint disease, with radiographic disease in 80% of people over the age of 75. High field-strength MRI and new techniques, such as T1, may provide a more sensitive means of assessing the degree of early damage to cartilage than plain film radiography or conventional MRI. The goal of this study is to determine the initial reproducibility and reliability of T1r mapping at 3-Tesla and determine the feasibility as a clinical tool. Reproducibility was studied sequentially on one machine as well as over time on multiple machines. These data are important to assure that accurate measurements are obtained and to determine if an external reference must be routinely evaluated for scanner calibration purposes.