David K W Yeung1, James F. Griffith1,
Yi-xiang Wang1, Jing Yuan1, Queenie Chan2,
Heather T. Ma1
1Diagnostic Radiology and Organ
Imaging, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong; 2MR,
Philips Healthcare, Wanchai, Hong Kong
Marrow
mesenchymal stem cells can differentiate along osteoblastic, adipocytic or
haematopoietic cell lines. Whether a shift occurs in stem cells
differentiation in osteoporosis is unknown. Iron-rich red marrow influences
T2* and fat-rich yellow marrow affects T2. Our goal was to verify whether
breathing oxygen may reduce the amount of deoxyhemoglobin (paramagnetic) in
marrow constituents thereby prolonging both T2* and T2. Our results showed
that, for the first time, both T2* and T2 of bone marrow increased after
oxygen inhalation. The larger δT2* compared to δT2 might reflects a
higher oxygen demand in the red marrow than the yellow marrow.
Keywords