Meeting Banner
Abstract #3205

Internal Gradient Evaluation in Spongy Bone Heel as a Potential Marker for Osteoporosis Disease

Mauro Rebuzzi1,2, Fabrizio Fasano3, Vincenzo Vinicola4, Gisela Hagberg5, Marco Di Mario6, Bruno Maraviglia3,7, Silvia Capuani, 18

1Physics, Sapienza University of Rome, Rome, Italy; 2CNR-INFM SOFT, Rome, Italy; 3IRCCS Santa Lucia Foundation, Rome, Italy; 4Rehabilitation Hospital, IRCCS Santa Lucia Foundation, Rome, Italy; 5Neuroimaging laboratory, IRCCS Santa Lucia Foundation, Rome, Italy; 6Radiology, IRCCS Santa Lucia Foundation, Rome, Italy; 7MARBILAB, Enrico Fermi Center, Rome, Italy; 8Physics, CNR-INFM SOFT, Rome, Italy

Aim of this work was to assess, in vivo, the potential ability of the internal gradient Gi to describe the spongy bone status when applied to postmenopausal women, and to identify the most promising heel locations to assess the presence of osteoporosis. ADC and Gi were measured from different regions in talus and calcaneus of each subject. ADC and Gi were correlated with the correspondent bone-mineral-density (BMD) from each volunteer. Our preliminary data confirm the ST as the most suitable region to detect osteoporosis, and Gi as the most sensitive parameter for an early diagnosis of osteoporosis