Mauro
Rebuzzi1,2, Fabrizio Fasano3, Vincenzo Vinicola4,
Gisela Hagberg5, Marco Di Mario6, Bruno Maraviglia3,7,
Silvia Capuani, 18
1Physics, Sapienza University of Rome,
Rome, Italy; 2CNR-INFM SOFT, Rome, Italy; 3IRCCS Santa
Lucia Foundation, Rome, Italy; 4Rehabilitation Hospital, IRCCS
Santa Lucia Foundation, Rome, Italy; 5Neuroimaging laboratory,
IRCCS Santa Lucia Foundation, Rome, Italy; 6Radiology, IRCCS Santa
Lucia Foundation, Rome, Italy; 7MARBILAB, Enrico Fermi Center,
Rome, Italy; 8Physics, CNR-INFM SOFT, Rome, Italy
Aim
of this work was to assess, in vivo, the potential ability of the internal
gradient Gi to describe the spongy bone status when applied to postmenopausal
women, and to identify the most promising heel locations to assess the
presence of osteoporosis. ADC and Gi were measured from different regions in
talus and calcaneus of each subject. ADC and Gi were correlated with the
correspondent bone-mineral-density (BMD) from each volunteer. Our preliminary
data confirm the ST as the most suitable region to detect osteoporosis, and
Gi as the most sensitive parameter for an early diagnosis of osteoporosis