Meeting Banner
Abstract #3243

In Vivo Fiber Tracking of Muscle Anatomy in Rodents (Oryctolagus Cuniculus) on a Clinical 3T MRI System

Daniel Gllmar1, Tobias Siebert2, Kay Leichsenring2, Carolin Kpper2, Reinhard Blickhan2, Jrgen R. Reichenbach1

1Medical Physics Group, Department of Diagnostic and Interventional Radiology, Jena University Hospital, Jena, Germany; 2Science of Motion, Institute of Sport Science, Friedrich-Schiller-University Jena, Jena, Germany

This work aims to facilitate diffusion tensor imaging on a clinical 3T MRI system in order to reconstruct the inner shank muscle architecture of rodents. Using a slightly modified EPI-DTI sequence and 3D anatomic scan, we were able to reconstruct the muscular structure within feasible scan time (approx. 45 min). The promising results will be validated by examining the myostructure using high-resolution (0.07 mm) 3D reconstruction techniques (Microscribe MLX) ex-vivo.