View-Order Consideration for Hyperpolarized C-13 Imaging with Radial Acquisition and Projection Reconstruction

Kang Wang¹, Eric Peterson², Jeremy Gordon¹, Krishna Kurpad³, Ian Rowland³, Matthew Erickson³, Sean Fain^1,3

Since hyperpolarized (HP) C-13 compounds exhibit non-equilibrium T1 decay and rapidly evolving spectral dynamics, fast imaging techniques such as radial acquisition have favorable characteristics which allow them to be combined with spectral imaging methods and thus follow the spectral dynamics. Due to the non-equilibrium of the magnetization, the acquired k-space will be modulated and the projection order needs to be designed to minimize spatial artifacts. In this work, we investigated, qualitatively and quantitatively, three different view-order schemes for 2D radial acquisitions. A superior scheme for minimizing artifacts in HP C-13 radial imaging was found.