Abstract #3287

Parallel MRI Acceleration of Dynamic and High Resolution Hyperpolarized 13C MRI

Lanette Friesen Waldner^1,2, Jian X. Wang³, Albert Chen⁴, Alexei Oriadov¹, Matthew Fox^1,5, Brian Rutt,^1,6, Timothy Scholl⁵, Giles Santyr^1,7, Charles McKenzie,¹²

¹Imaging Research Laboratories, Robarts Research Institute, London, ON, Canada; ²Medical Biophysics, The University of Western Ontario, London, ON, Canada; ³Global Applied Science Laboratory, GE Healthcare, London, ON, Canada; ⁴GE Healthcare, Toronto, ON, Canada; ⁵Physics and Astronomy, The University of Western Ontario, London, ON, Canada; ⁶Diagnostic Radiology and Richard M Lucas Center for Imaging, Stanford University, Stanford, CA, United States; ⁷Medical Imaging, The University of Western Ontario, London, ON, Canada

Imaging with hyperpolarized agents requires extremely fast imaging techniques as the hyperpolarized state only lasts for tens of seconds. Parallel MRI reduces image encoding time, allowing hyperpolarized images to be acquired faster, or at higher spatial resolution than would otherwise be possible. Using a custom eight-element ¹³C array to acquire images of a rat following injection of hyperpolarized ¹³C enriched pyruvic acid, we demonstrate accelerated imaging, using self calibrated PMRI to achieve high spatial and temporal resolutions. These results represent the first hyperpolarized ¹³C PMRI experiments conducted with a receive array with more than 4 elements.