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Abstract #3287

Parallel MRI Acceleration of Dynamic and High Resolution Hyperpolarized 13C MRI

Lanette Friesen Waldner1,2, Jian X. Wang3, Albert Chen4, Alexei Oriadov1, Matthew Fox1,5, Brian Rutt, 1,6, Timothy Scholl5, Giles Santyr1,7, Charles McKenzie, 12

1Imaging Research Laboratories, Robarts Research Institute, London, ON, Canada; 2Medical Biophysics, The University of Western Ontario, London, ON, Canada; 3Global Applied Science Laboratory, GE Healthcare, London, ON, Canada; 4GE Healthcare, Toronto, ON, Canada; 5Physics and Astronomy, The University of Western Ontario, London, ON, Canada; 6Diagnostic Radiology and Richard M Lucas Center for Imaging, Stanford University, Stanford, CA, United States; 7Medical Imaging, The University of Western Ontario, London, ON, Canada

Imaging with hyperpolarized agents requires extremely fast imaging techniques as the hyperpolarized state only lasts for tens of seconds. Parallel MRI reduces image encoding time, allowing hyperpolarized images to be acquired faster, or at higher spatial resolution than would otherwise be possible. Using a custom eight-element 13C array to acquire images of a rat following injection of hyperpolarized 13C enriched pyruvic acid, we demonstrate accelerated imaging, using self calibrated PMRI to achieve high spatial and temporal resolutions. These results represent the first hyperpolarized 13C PMRI experiments conducted with a receive array with more than 4 elements.