Douglas E. Befroy1, Peter B. Brown1,
Kitt F. Petersen1, Gerald I. Shulman1, Douglas L.
at increasing B0 field strengths is accompanied by an enhancement
in signal/noise and spectral resolution. However, the concomitant increase in
RF power mitigates these effects for J-coupled metabolites in-vivo since
decoupling schemes tend to be prohibited by SAR restrictions. By taking
advantage of the higher SAR limits for peripheral tissues and by using
relatively small coil geometries to maximize the efficiency of RF
transmission, we demonstrate that 1H decoupled 13C-MRS
is feasible in superficial human skeletal muscles at 7T.