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Abstract #3313

Simultaneous MSC-SelMQC Mapping of Polyunsaturated Fatty Acids (PUFA), Lactate and Choline in Tissues Containing High Concentration of Mobile Lipid

Qiuhong He1,2

1Radiology, University of Pittsburgh, Pittsburgh, PA, United States; 2Bioengineering, University of Pittsburgh, Pittsburgh, PA, United States

The Selective Multiple Quantum Coherence transfer (Sel-MQC) method is modified for simultaneous mapping of polyunsaturated fatty acids (PUFA), lactate and choline in three unique Molecular Specific Coherence (MSC) transfer pathways with complete lipid and water suppression in a single scan. Choline signal is also detectable in a second spin echo to enhance lipid suppression. The method can be applied to study animal tumor models and human breast cancer or other extracranial cancers.