Kuan-Ting Wu1, Chen-Shuan Huang1,
Stefan Posse2,3, Shang-Yueh Tsai1
1Department of Electrical Engineering,
Chang Gung University, Tao Yuan, Taiwan; 2Department of Neurology,
University of New Mexico School of Medicine, Alberquerque, NM, United States;
3Department of Electrical & Computer Engineering, University
of New Mexico , Alberquerque, NM, United States
A
processing procedure is proposed to do the tissue type correction for
metabolite concentrations on spectroscopic imaging. Tissue segmentation is
first done on 3D high resolution T1 images (MPRAGE). Image registration
provided by SPM8 software is then applied to generate GM, WM and CSF
probability maps at corresponding slice of spectroscopic imaging for the
correction of metabolite concentrations. Our results showed that
concentration correction can be done well on two segmentation methods and
integration of SPM into tissue type correction is useful for future
application of MRSI at different locations and slice orientations.
Keywords