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Abstract #3351

T2 Determination of the J-Coupled Methyl Protons of Tibial Bone Marrow Lipids at 3 T

Atiyah Yahya1,2, B. Gino Fallone1,2

1Department of Medical Physics, Cross Cancer Institute, Edmonton, Alberta, Canada; 2Department of Oncology, University of Alberta, Edmonton, Alberta, Canada

Magnetic resonance spectroscopy of lipids has provided insight into a number of diseases. The methylene (CH2) to methyl (CH3) lipid proton ratio is a useful quantity. For accurate calculations of this ratio, reliable estimates of the T2 values of the protons are required. Determining a representative T2 for the methyl protons is challenging because of J-coupling contributions. In this work, we show how the T2 of the methyl protons of lipids can be measured at 3 T with minimal contributions from J-coupling evolutions. The efficacy of the technique was verified on tibial bone marrow of four healthy volunteers.