Atiyah Yahya1,2,
B. Gino Fallone1,2
1Department of Medical Physics, Cross
Cancer Institute, Edmonton, Alberta, Canada; 2Department of
Oncology, University of Alberta, Edmonton, Alberta, Canada
Magnetic
resonance spectroscopy of lipids has provided insight into a number of
diseases. The methylene (CH2) to
methyl (CH3) lipid proton ratio is a useful quantity. For accurate calculations of this ratio,
reliable estimates of the T2 values of the protons are required. Determining a representative T2 for the
methyl protons is challenging because of J-coupling contributions. In this work, we show how the T2 of the
methyl protons of lipids can be measured at 3 T with minimal contributions
from J-coupling evolutions. The efficacy
of the technique was verified on tibial bone marrow of four healthy
volunteers.