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Abstract #3431

Spontaneous Low-Frequency Fluctuations in the Thalamus: Evidence from 3T and 7T Resting-State FMRI

Lin Tang1, Yulin Ge1, Daniel Sodickson1, Kellyanne Mcgorty1, Joseph Reaume1, Robert Grossman1

1Department of Radiology, The Center for Biomedical Imaging of New York University, New York City, NY, United States

The thalamus, as the centrally located relay station for transmitting information throughout the brain, participates in communication with many associative brain regions and involves global multi-functional pathways. The purpose of this study was to investigate whether the 7T resting-state functional scans can give us more information on this low frequency resting state network (RSN) associated with thalamic function. This study demonstrates for the first time, the thalamic functional network during resting state obtained from both 3T and 7T scans in healthy volunteers. Thalamus was implicated to be primarily involved with motor control based on results from 3T scans. Meanwhile thalamus was showed to be functionally related to a number of more brain areas from 7T scans. The 7T scan verified the larger functional network of thalamus in brain neural activity and demonstrated that the thalamus is involved in regulating the transmission of information regarding visual, motor control, perception, some cognitive functioning and so forth.