Benedikt A.
Poser1,2, David G. Norris1,2
1Donders Institute for Brain, Cognition
and Behaviour, Radboud University Nijmegen, Nijmegen, Netherlands; 2Erwin
L. Hahn Institute for Magnetic Resonance Imaging, University Duisburg-Essen,
Essen, Germany
Using
a recently developed multi-slice variant of VASO that enables single-shot
whole-brain coverage by virtue of a 3D GRASE readout, we here present the
first application of VASO to an fMRI study with a real cognitive
stimulation paradigm on twelve subjects. Within acceptable measurement times
of ~12 min, the numerous clusters brain activation during a Stroop color-word
matching task could be detected reliably both on the group (N=12) and single
subject level, as evident from a qualitative comparison with separately
acquired BOLD data and literature reports.