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Abstract #3487

First Application of Whole Brain CBV Weighted FMRI to a Cognitive Stimulation Paradigm: Robust Activation Detection in a Stroop Task Experiment Using 3D GRASE VASO

Benedikt A. Poser1,2, David G. Norris1,2

1Donders Institute for Brain, Cognition and Behaviour, Radboud University Nijmegen, Nijmegen, Netherlands; 2Erwin L. Hahn Institute for Magnetic Resonance Imaging, University Duisburg-Essen, Essen, Germany

Using a recently developed multi-slice variant of VASO that enables single-shot whole-brain coverage by virtue of a 3D GRASE readout, we here present the first application of VASO to an fMRI study with a real cognitive stimulation paradigm on twelve subjects. Within acceptable measurement times of ~12 min, the numerous clusters brain activation during a Stroop color-word matching task could be detected reliably both on the group (N=12) and single subject level, as evident from a qualitative comparison with separately acquired BOLD data and literature reports.