Meeting Banner
Abstract #3543

Cortical and Subcortical Activations by High Field FMRI for Different Sensory Stimuli

Basavaraju G. Sanganahalli1, Peter Herman1,2, Christopher J. Bailey1,3, Douglas L. Rothman1,4, Hal Blumenfeld5,6, Fahmeed Hyder1,4

1Diagnostic Radiology, Yale University, New Haven, CT, United States; 2Human Physiology, Semmelweis University, Budapest, Hungary; 3Center of Functionally Integrative Neuroscience, Aarhus University, Denmark; 4Biomedical Engineering, Yale University; 5Neurology, Yale University, New Haven, CT, United States; 6Neuroscience, Yale University

We used 11.7T fMRI to study subcortical activations during tactile and non-tactile stimuli. Forepaw stimulation activates medial portions of the lateral thalamic nucleus. Whisker stimulation activates broader regions within the thalamus. Visual stimulation activates superior colliculus and lateral geniculate nucleus. Comparison with atlas-based anatomy shows that thalamic activations were in different parts of ventroposterior and laterodorsal nuclei, as well as medial and dorsal parts of the geniculate nucleus, anterior and posterior regions of the pretectal nucleus, and the periaqueductal gray region. Mainly top layers of the superior colliculus were activated. These subcortical regions are implicated in integration of sensory stimuli