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Abstract #3567

Quantitative Assessment of Left Ventricular Function Using Cardiac Phase-Contrast and Cine Magnetic Resonance Imaging Comparison with Pressure-Volume Loops Analysis: In Vivo Validation on a Swine Model

Hung-Yu Lin1, Fei Wang2, Waiel Almoustadi3, Bo Xiang2, Trevor Lee3, Rakesh Arora3, Scott B. King2, Boguslaw Tomanek2, Darren Freed3, Ganghong Tian2

1Institute for Biodiagnostics, National Research Council of Canada, Winnipeg, Manitoba, Canada; 2Institute for Biodiagnostics, National Research Coincil of Canada; 3Saint Boniface General Hospital, Winnipeg, Manitoba, Canada

Noninvasive PC-MRI and cine MRI have been recognized as a valuable and accurate technique to evaluate hemodynamics and heart function. Previous clinical studies suggest that evaluation of the passive relaxation properties serves as a useful indicator of quantitative contractility and function without the influence of relative ventricular load. To our knowledge, the correlation of LV function obtained from noninvasive PC-MRI, cine MRI and invasive P-V loops relation has not been investigated and reported. The aim of the present study was to determine the validity of PC-MRI, cine MRI in the assessment of LV function comparing with dynamic P-V loops analysis.