Elodie Breton1, Daniel Kim1, Sohae Chung1, Leon Axel1
1Research Radiology - Center for
Quantitative analysis of first-pass contrast-enhanced cardiac perfusion MRI requires the signal-time curve be converted to Gd-DTPA concentration-time curve. A theory-based single-point T1 measurement method has been proposed and validated in phantoms at 1.5T. In this study at 3T, the sensitivity to B1 variations and blood inflow of the single-point T1 mapping method was first evaluated depending on its linear or centric k-space trajectory. Then, the centric k-space trajectory T1 mapping pulse sequence was validated in vivo against a multi-point saturation recovery T1 measurement method in the left ventricular myocardium and cavity.