MR-Based PET Attenuation Correction for Neurological Studies Using Dual-Echo UTE Sequences

Ciprian Catana¹, Andre van der Kouwe¹, Thomas Benner¹, Michael Hamm², Christian J. Michel², Matthias Fenchel², Larry Byars², Matthias Schmand², Alma Gregory Sorensen¹

Attenuation correction is a required step not only for obtaining quantitative data, but also for performing meaningful qualitative image analysis. In order to achieve the necessary quantification for accurate quantitative neurological studies, three main components must be identified: water-based structures, bone tissue and air-filled cavities. DUTE sequences can potentially be used for bone/air segmentation. An MR-DUTE-based AC method could in principle provide accurate estimation of the radiotracer concentration in a particular voxel. Implementing an accurate MR-based AC will allow us take advantage of the improved quantitative capabilities of the combined MR-PET scanner.