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Abstract #3954

fMRI Investigations on an MR-PET System During Simultaneous PET Scanning: Technical Considerations

Joachim Bernhard Maria Kaffanke1, Irene Neuner1,2, Tony Stcker1, Lutz Tellmann1, Karl-Joseph Langen1, Hans Herzog1, N. Jon Shah1,2

1Institute of Neurosciences and Medicine 4, Medical Imaging Physics, Forschungszentrum Jlich GmbH, 52425 Juelich, Germany; 2Faculty of Medicine, Department of Neurology, RWTH Aachen University, 52074 Aachen, Germany

The new technology of hybrid MR-PET scanners offers great opportunities for the investigation of scientific questions and clinical diagnosis that are related to metabolism as well as function and structure of the brain. Despite the fact that the implementation of a PET ring inside the bore of a modern whole body MR scanner is demanding the benefits in terms of scan time reduction as well as spatial and temporal co-registration speak for the combination of these complementary technologies. In this feasibility study we demonstrate the simultaneous acquisition of FET-PET and fMRI data in human subjects with brain tumours.