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Abstract #3955

Improved PET Data Quantification in an Integrated Brain MR-PET Scanner

Ciprian Catana1, Thomas Benner1, Andre van der Kouwe1, Michael Hamm2, Daniel B. Chonde1, Christian J. Michel2, Larry Byars2, Georges El Fakhri3, Nathaniel M. Alpert3, Matthias Schmand2, Alma Gregory Sorensen1

1MGH, Radiology, A.A. Martinos Center for Biomedical Imaging, Charlestown, MA, United States; 2Siemens Healthcare; 3Radiology, MGH, Division of Nuclear Medicine & Molecular Imaging, United States

Simultaneous MR-PET data acquisition immediately brings to mind the possibility of improving the performance of one instrument by using the information obtained from the other modality. A number of aspects have to be considered in PET for obtaining a correct quantitative measure of the activity concentration in a specific voxel. Examples include the attenuation and motion correction and the arterial input function estimation. The accuracy of these methods, in principle, could be improved by including the MR information.