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Abstract #3972

Bias Free Estimates of the Diffusional Kurtosis in Two Minutes: Avoid Solving the Kurtosis Tensor

Jimmy Ltt1,2, Markus Nilsson2, Sara Brockstedt3, Ronnie Wirestam2, Freddy Sthlberg2,4

1Center for Medical Imaging and Physiology, Lund University Hospital, Lund, Sweden; 2Department of Medical Radiation Physics, Lund University, Lund, Sweden; 3Radiation Physics, Lund University Hospital, Lund, Sweden; 4Department of Diagnostic Radiology, Lund University, Lund, Sweden

Diffusion kurtosis imaging provides additional information as compared to diffusion tensor imaging. Due to the long scan times, required to solve the kurtosis tensor, diffusion kurtosis measurements are not always clinical feasible. In this study, we show that a bias free kurtosis value can be estimated through an optimized encoding scheme within a clinically feasible time of two minutes.