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Abstract #4009

Fast Normalization of Probabilistic Tractography

Stephen Edward Jones1,2, Kenneth Sakaie

1Neuroradiology, Cleveland Clinic, Cleveland, OH, United States

Numerical computation of track density using probabalistic DWI can be inefficient, particularly for distant points. We present a method that uses a partial differential equation approach (Laplace's equation) to solve the special isotropic case of probablistic tracking. This provides a rapid solution for any two points within the brain, with arbitrary accuracy. This solution can be coupled with anisotropic probablistic tracking to obtain scalar measures of connectivity.