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Abstract #4010

A Minimal Model, Data-Driven Approach to Tractography

Angela Downing1, Daniel Rueckert2, A David Edwards, 1,3, Jo V. Hajnal1

1Robert Steiner MRI Unit, Imaging Sciences Department, MRC Clinical Sciences Centre, Hammersmith Hospital, Imperial College London, London, United Kingdom; 2Visual Information Processing Group, Department of Computing, Imperial College London, London, United Kingdom; 3Department of Paediatrics, Imaging Sciences Department, MRC Clinical Sciences Centre, Hammersmith Hospital, Imperial College London, London, United Kingdom


We present a minimal model approach to tractography using the diffusion-weighted MRI measurements to represent samples from a diffusivity profile. Using phantom data we show that it is possible to accurately reconstruct the fibre structure between regions of interest by simulating the diffusion process that gives rise to the data.