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Abstract #4077

Measurement Stability in Arterial Spin Labeling Investigated Using Multiple Sites

Jerod Michael Rasmussen1, Tom Liu2, Bryon Mueller3, Greg Brown2, Christina Wierenga2, Gary H. Glover4

1University of California, Irvine, Irvine, CA, United States; 2University of California, San Diego; 3University of Minnesota; 4Stanford University

This study uses multiple scanners to investigate the effect of varying the number of repetitions used in CBF measurement of Gray Matter tissue (GM) and establishes recommendations for the minimum scan time necessary for a stable calculation. Data was combined across 2 traveling subjects studies and the number of repetitions used for analysis ranged from 16 to 104 in control/tag pairs. Gray Matter masked CBF statistics showed an expected inverse decrease in noise with acquisitions and converged on a recommendation of 92 repetitions for a stable CBF measurement.