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Abstract #4092

Background Correction of Phase-Based Arterial Input Functions

Anders Garpebring1, Patrik Brynolfsson1, Ronnie Wirestam2, Nils stlund3, Mikael Karlsson1

1Radiation Sciences, Ume University, Ume, Sweden; 2Medical Radiation Physics, Lund University, Lund, Sweden; 3Biomedical Engineering and Informatics, Ume University Hospital, Ume, Sweden

Phase sensitive MRI has shown great potential for quantification of the Arterial Input Function (AIF). However, motion induced phase artefacts are problematic for in-vivo measurements and must be compensated for. The purpose of this study was to compare three different background ROI selection procedures for compensation of phase errors. Results showed that efficient correction of motion induced phase shifts requires a background ROI placed close to the vessel from which the AIF is sampled. Some further improvement can also be achieved by tracking and compensating for any in-plane motion of the vessel.