Stephan Ulmer1, Gesa Hartwigsen2,
Michael Helle1, Olav Jansen1, Maximillian Hubertus
Mehdorn3, Arya Nabavi3
1Institute of Neuroradiology,
University Hospital of Schleswig-Holstein, Kiel, Germany; 2Department
of Neurology, University Hospital of Schleswig-Holstein, Kiel, Germany; 3Department
of Neurosurgery, University Hospital of Schleswig-Holstein, Kiel, Germany
Dynamic
susceptibility contrast MRI (DSC-MRI) was applied in a model with an
air-fluid-level and in a flow phantom to assess possible artifacts of an
intraoperative setting. In 6 patients with glioblastoma multiforme iDSC-MRI
was performed. In both models there were only minor distortions. In 5
patients complete removal of the lesion was already achieved by the time of
iDSC-MRI. In the remaining case tumor could be depicted that demonstrated
identical perfusion ratio as in the preoperatively acquired scans. DSC-MRI is
technically feasable intraoperatively and enables a differentiation of
residual tumor from contrast-enhancement caused by surgical manipulation in
these intraoperative MRIs.
Keywords