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Abstract #4123

Focal Spot Visualization in MRgFUS of the Breast: MR-ARFI Vs. T1-Weighted FSE

Elena Kaye1,2, Rachel Rinat Bitton1, Kim Butts Pauly1

1Radiology, Stanford University, Palo Alto, CA, United States; 2Electrical Engineering, Stanford University, Palo Alto, CA, United States

The goal of this study was to compare MR-ARFI and T1-w FSE approaches to focal spot visualization during breast MRgFUS. An ex vivo human breast tissue sample was imaged on a 3T MRI scanner equipped with an InSightec HIFU system. MR-ARFI displacement were compared with the magnitude difference images obtained by subtraction of FSE images with ultrasound on and off. The results of the study showed that both T1-w imaging and MR-ARFI allow visualization of the FUS focal spot., however, the MR-ARFI approach deposits 10 times less ultrasound energy and gives 3 times greater SNR than an FSE-based approach.