Meeting Banner
Abstract #4184

Fluorinated Cyclodextrin as a Novel 19F Contrast Agent for Labeling Cells

Florian Schmid1, Maria Becker2, Marc Hotfilder3, Bart-Jan Ravoo2, Cornelius Faber1

1Department for Clinical Radiology, University Hospital Mnster, Mnster, Germany; 2Organic Chemistry Institute of the Westflische Wilhelms-Universitt Mnster, Mnster, Germany; 3Department of Pediatric Hematology and Oncology, University Children's Hospital Mnster, Mnster, Germany

Fluorinated Cyclodextrins are interesting candidates for novel MR contrast agents for cell labelling as they are soluble in water and contain lots of 19F atoms that contribute to a single spectral line. Results from first cell labeling experiments performed on Ewing's sarcoma cells are presented; 19F MR images acquired on a clinical 3T MRI scanner are shown.