Shiou-Ping Lee1, Jie-Zhi Cheng2,
Wen-Yang Chiang3, Chung-Ming Chen2, Kao-Lun Wang1
1Department of Medical Imaging and
Technology, Far Eastern Memorial Hospital, Taipei, Taiwan; 2Institute
of Biomedical Engineering, National Taiwan University, Taipei, Taiwan; 3Center
for Optoelectronic Biomedicine, National Taiwan University Medical College,
Taipei, Taiwan
None
of systemic lupus erythematosus (SLE) studies examined diffusion tensor
imaging (DTI) and volumetric measurement in the same groups. This paper aimed
to investigate the effect of central nervous system (CNS) involvement in SLE
patients on two diffusion parameters, i.e., fractional anisotropy (FA) and
mean diffusivity (MD), and one volumetric measurement, i.e., volume. To
accurately define the corpus callosum boundaries, an automatic segmentation
algorithm, cell-competition method, was adopted to delineate the boundaries
of the corpus callosum on mid-sagittal FA maps to calculate FA, MD and volume
of corpus callosum.