Pallab Bhattacharyya1, Erik Beall1,
Mark Lowe1, Micheal Phillips1, David Muzina1
1Cleveland Clinic, Cleveland, OH,
United States
Gamma
amino butyric acid (GABA) level in anterior cingulate is known to be reduced
in depression patients. Electroconvulsive therapy (ECT) is a commonly used
treatment for major depressive episodes (MDE). Using 1H
spectroscopy we have measured anterior cingulate GABA level 2 weeks before
and 1-2 weeks after ECT treatment in MDE patients. Our preliminary data show
an increase in anterior cingulate GABA level following ECT in MDE patients.
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