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Abstract #4475

Probabilistic Fiber Tracking from the Pre-SMA and SMA Proper: Implications for Language and Motor White Matter Networks

Kyung K. Peck1, Seyedeh Jenabi2, Robert Young, Lucas Parra2, Andrei Holodny

1Medical Physics and Radiology, Memorial Sloan-Kettering Cancer Center, New York, United States; 2City University of New York

In this study, we seek to expand on this study by using diffusion tensor imaging to compare the pattern of white matter fibers originating from two different fMRI guided seed regions; the pre-SMA and the SMA-proper defined by fMRI language and motor paradigm respectively. We hypothesized that pre-SMA seed derived from the language paradigm will connect more readily to the frontal areas known to be associated with language function including Brocas Area