Sanja Budisavljevic1, Flavio Dell'Acqua,
Stephanie Forkel, Michel Thiebaut de Schotten, Marco Catani
1Department of Forensic and
Neurodevelopmental Sciences, Institute of Psychiatry, King's College, London,
United Kingdom
Using
DT-MRI tractography we investigated lateralisation of perisylvian pathways
with age in Aspergers Syndrome. We observed that the indirect pathway of the
arcuate fasciculus shows abnormal development with age in people with
Aspergers syndrome compared to controls. This suggests that abnormalities in
white matter development may be a key feature of autism spectrum disorders
and may explain impairments in language and communication.