Iris Y. Zhou1,2, April Mei Kwan Chow1,2, Kevin C. Chan1,2, Condon Lau1,2, Ed X. Wu1,2
1Laboratory of Biomedical Imaging and Signal Processing, The University of Hong Kong, Pokfulam, Hong Kong SAR, China; 2Department of Electrical and Electronic Engineering, The University of Hong Kong, Pokfulam, Hong Kong SAR, China
In the present study, we use in vivo MEMRI to detect the cerebellar activation in mouse brain induced by voluntary wheel running. The preliminary result of our study shows that after voluntary wheel-running exercise, mouse cerebellum regions such as vermis, Crus I and II of ansiform lobule and caudal pontine reticular nucleus are significantly activated compared to the sedentary animals. This difference can be feasibly detected by MEMRI, suggesting the great potential of MEMRI as an in vivo probe for mapping neural activity.