Xiao Hong Ma1, Chun Wu Zhou1, Fei
Sun2, Xin Ming Zhao1, Han Ouyang1, Hong Mei
Zhang1
1Diagnostic Radiology, Cancer Hospital,
Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing,
China; 2Shanghai Guided Medical Scientific Co. Ltd., Shanghai,
China
Our
study target to semi-quantify the perfusion parameters of normal pancreas and
pancreatic carcinoma with three-dimension (3D) high spatial and time
resolution dynamic contrast enhanced (DCE) MRI on a 3.0T MR system. 31
patients who need abdomen contrast enhancement scan but with normal pancreas
and 34 pancreatic carcinoma patients underwent DCE-MRI on a 3.0T MR system
with 8-channel body coil. The perfusion parameters were measure including
signal enhancement ratio at 30 seconds and 90 seconds after injection (SER30,
SER90), positive enhancement integral (PEI), time to peak (TTP) and maximum
slope of increase (MSI). There is no regional perfusion difference between
the head, body and tail of normal pancreas, while there is significant
difference between lesion and non-lesion area of pancreatic carcinoma, and
between normal pancreas and non-lesion area of pancreatic carcinoma.
Keywords