Kyung Ah Kim1, Mi-Suk Park1, Eun
Ju Kim2, Myeong-Jin Kim1, Jin-Young Choi1,
Hye-Suk Hong1, Ki Whang Kim1
1Radiology, Severance Hospital, Yonsei
University College of Medicine, Seoul, Korea, Republic of; 2Clinical
science, MR, Philips Healthcare, Seoul, Korea, Republic of
We
investigated the effect of the oxygen inhalation on relaxation times of T1 in
abdominal solid organs, including liver, pancreas, spleen, and kidney. The
inhalation of oxygen caused T1 shortening in the pancreas, kidney and spleen,
which have predominant arterial blood supply, whereas no significant effect
was noted in the liver, which has predominant portal venous blood supply. Our
results indicate that MRI is feasible to detect changes with oxygen
inhalation, which differs considerably among organs, in a noninvasive
fashion. As a clinical application, the effect of oxygen on various normal
and pathologic tissues may be used as a biomarker of arterial flow, oxygen
delivery to organs, and hypoxic status.
Keywords