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Abstract #4567

Effects of Oxygen Inhalation on T1 Relaxation Times in Abdominal Solid Organ

Kyung Ah Kim1, Mi-Suk Park1, Eun Ju Kim2, Myeong-Jin Kim1, Jin-Young Choi1, Hye-Suk Hong1, Ki Whang Kim1

1Radiology, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea, Republic of; 2Clinical science, MR, Philips Healthcare, Seoul, Korea, Republic of

We investigated the effect of the oxygen inhalation on relaxation times of T1 in abdominal solid organs, including liver, pancreas, spleen, and kidney. The inhalation of oxygen caused T1 shortening in the pancreas, kidney and spleen, which have predominant arterial blood supply, whereas no significant effect was noted in the liver, which has predominant portal venous blood supply. Our results indicate that MRI is feasible to detect changes with oxygen inhalation, which differs considerably among organs, in a noninvasive fashion. As a clinical application, the effect of oxygen on various normal and pathologic tissues may be used as a biomarker of arterial flow, oxygen delivery to organs, and hypoxic status.