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Abstract #4569

Characterization of Cirrhotic Nodules with Gadoxetic Acid-Enhanced MR Imaging: The Efficacy of Hepatocyte-Phase Imaging

Chen-Te Chou1,2, Ran-Chou Chen2,3

1Radiology, Chang-Hua Christian Hospital, Chang-Hua, Taiwan; 2Biomedical Imaging and Radiological Science, National Yang-Ming Medical University, Taipei, Taiwan; 3Radiology, Taipei City Hospital, Taipei, Taiwan

The study was to evaluate the efficacy of hepatocyte-phase imaging in characterization of focal hepatic lesions among cirrhotic liver using gadoxetic acid enhanced MRI. Our results revealed SNRs/CNRs of HCC were significantly decreased in hepatocyte phase (P<0.05) and the benign DN showed no significant difference (P>0.05). Severe additional HCC were diagnosed by hepatocyte-phase imaging. The diagnostic performance is significantly higher in the imaging set with hepatocyte-phase imaging (P=0.016). In conclusion, combination of gadoxetic acid-enhanced dynamic study and hepatocyte-phase imaging could provide better diagnostic performance than dynamic study only in characterization of focal liver lesion among cirrhotic liver.