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Abstract #4601

3D Hyperpolarized 3He Imaging of Human Lung with Isotropic Spatial Resolution Using 3D-Cones

Jian-Xiong Wang1, Alexei V. Ouriadov2, Jeffrey A. Stainsby3, Grace E. Parraga2, Giles Santyr2,4

1Applied Science Laboratory, GE HEALTHCARE, London, ON, Canada; 2Robarts Research Institute, The University of Western Ontario, London, ON, Canada; 3Applied Science Laboratory, GE HEALTHCARE, Toronto, ON, Canada; 4Dept. of Medical Biophysics, The University of Western Ontario, London, ON, Canada

A true 3D isotropic spatial resolution imaging method for Hyperpolarized He-3 human lung imaging using 3D-cones sequence is presented. The isotropic voxel size improves accuracy for co-registration, lung volume measurement and analysis for abnormalities in the lung.