Ignacio
Rodriguez1,2, Laura Carrero-Gonzalez, 1,3, Thomas
Kaulisch3, Detlef Stiller3, Jose Manuel Perez-Sanchez4,
Jesus Ruiz-Cabello1,2
1Instituto
de Estudios Biofuncionales, Universidad Complutense, Madrid, Spain; 2CIBER
de Enfermedades Respiratorias, Madrid, Spain; 3Boehringer
Ingelheim Pharma, Biberach an der Riss, Germany; 4Univ. Paris-Sud,
CNRS, Orsay, France
Using
long-range diffusion MRI, ADC of rats with induced emphysema in one lobe has
been performed. The results show a statistically significant increase of ADC
in the emphysematous lobe at breath-hold, whereas no significant difference
is seen at end expiration. Collateral ventilation could play a role in these
results. The increase seen at breath-hold agrees with the results found by
other workers.
Keywords